What Is GHK-Cu? The Copper Peptide Explained for Researchers
GHK-Cu, often called “copper peptide,” is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK). It is one of the most studied small peptides in research on copper biology. This guide explains its structure, discovery, research uses and handling.
What is GHK-Cu?
GHK is a naturally occurring tripeptide first identified in human plasma in the early 1970s by researcher Loren Pickart. GHK binds copper(II) ions with high affinity, and the resulting complex, GHK-Cu, is the form most often studied. In solid form GHK-Cu is blue, a visible sign of its copper content.
GHK-Cu chemical profile
| Compound | Copper(II) glycyl-L-histidyl-L-lysine |
|---|---|
| Peptide sequence | Gly-His-Lys (GHK) |
| CAS number | 89030-95-5 |
| Molecular formula | C14H22CuN6O4 |
| Molecular weight | ≈401.9 g/mol |
| Typical research form | Lyophilized blue solid in a sealed vial |
Why researchers study GHK-Cu
Because of its copper-binding chemistry, GHK-Cu is studied in in-vitro and animal models of copper transport, extracellular-matrix biology and gene-expression signaling. It also appears as a component in multi-peptide research blends.
GHK vs. GHK-Cu
GHK is the free tripeptide. GHK-Cu is the same tripeptide complexed with copper(II). Molecular weights reported for GHK-Cu vary slightly (about 401.9–403 g/mol) depending on how the copper complex and its counter-ions are represented, so researchers should check the specification sheet for the exact form supplied.
Regulatory status
GHK-Cu sold as a research peptide is a laboratory material, not a drug or a dietary supplement, and is not for human or veterinary use.
Storage and handling
- Keep sealed vials at −20 °C, dry and protected from light.
- Note the color of the solid on receipt; GHK-Cu should be blue.
- Log lot numbers and minimize freeze-thaw cycles.
What to look for in a GHK-Cu supplier
- Third-party testing of every lot for purity and identity.
- A stated amount per vial (for example 50 mg or 100 mg) and lot traceability.
- Research-use-only labeling and no cosmetic or human-use claims.
GHK-Cu at Attestryn
Attestryn supplies GHK-Cu 50 mg as a sealed, lyophilized research vial. Every lot is third-party tested before release and ships from within the United States. You can also browse related compounds such as KPV and BPC-157.
GHK-Cu FAQ
Why is GHK-Cu blue?
The blue color comes from the copper(II) ion bound to the GHK peptide.
Who discovered GHK?
GHK was first identified in human plasma in the early 1970s by Loren Pickart.
Is GHK-Cu for human use?
Attestryn GHK-Cu is sold for laboratory research use only and is not for human or veterinary use.
This article is for educational and informational purposes about laboratory research materials. Attestryn products are sold for laboratory research use only. They are not drugs, foods, cosmetics or dietary supplements, are not for human or veterinary use, and have not been evaluated by the FDA. Attestryn does not provide dosing, reconstitution or administration information.